Does TRT Affect Fertility and Can You Preserve It While on Therapy? 2025
Testosterone Replacement Therapy (TRT) significantly suppresses sperm production in 90% of men within 6 months, according to reproductive endocrinology research (Journal of Clinical Endocrinology & Metabolism, 2023). The exogenous testosterone disrupts the Hypothalamic-Pituitary-Gonadal Axis, reducing Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) to near-zero levels. Whereas standard TRT protocols typically cause azoospermia or severe oligospermia,…