Prescription TRT vial next to OTC testosterone booster supplement pills for hormone therapy comparison.

What Is TRT? Understanding the Difference Between Testosterone Replacement Therapy and Over-the-Counter Boosters

TRT (Testosterone Replacement Therapy) is a prescription-based hormone therapy that restores testosterone levels using clinically dosed medication under medical supervision. Over-the-counter (OTC) testosterone boosters are dietary supplements sold without a prescription that claim to stimulate the body’s natural testosterone production. The core difference lies in regulation, dosage precision, and clinical oversight. Why This Distinction Matters Low…